Ira S. Hofer, MD is a practicing anesthesiologist and clinical informaticist at The Icahn School of Medicine at Mount Sinai and the founder and President of Extrico Health. Dr. Hofer has been working in big data analytics with electronic health record (EHR) data for over 15 years. He has held a variety of roles at multiple world-renowned hospital systems building and deploying AI (Artificial Intelligence) models and overseeing analytics for system wide and departmental programs. He currently holds joint appointments in Anesthesiology, Medicine at the Charles Bronfman Institute for Personalized Medicine and is the inaugural director of the Rapid Randomized Trial Unit in the CBIM which is focused on deploying AI models into clinical care using study designs to measure efficacy.
Dr. Hofer’s research interests involve leveraging the data from the EHR to understand, quantify and mitigate risk in the perioperative period. His work includes some of the first papers to apply machine learning techniques for perioperative outcome prediction and has been featured on the cover of both Anesthesiology and Anesthesia & Analgesia. Ira has a K01 from the National Heart Lung and Blood institute, and funding from the NIA funded IMPACT Collaboratory for a pragmatic trial to reduce postoperative delirium using an AI driven decision support model. He also serves as an associate editor for Anesthesia & Analgesia. His current research focus is on creating featurization techniques to incorporate a wide range of EHR data into machine learning models to improve discrimination and calibration and establishing multi-center perioperative collaboratives to build more generalizable models and enhance health equity.